| Date | Opp | Result | FO | FO% | GB |
|---|---|---|---|---|---|
| 2022-05-01 | @ Duke Blue Devils | L 11–19 | 7-9 | 43.8 | 3 |
| 2022-04-21 | @ Notre Dame Fighting Irish | L 5–12 | 0-3 | 0.0 | 0 |
| 2022-04-16 | Syracuse Orange | W 14–13 | 3-4 | 42.9 | 1 |
| 2022-04-09 | @ Virginia Cavaliers | L 4–11 | 11-10 | 52.4 | 7 |
| 2022-04-02 | Duke Blue Devils | L 6–15 | 7-9 | 43.8 | 3 |
| 2022-03-26 | Bellarmine Knights | W 15–8 | 11-4 | 73.3 | 3 |
| 2022-03-11 | Virginia Cavaliers | L 11–15 | 11-10 | 52.4 | 7 |
| 2022-03-05 | Denver Pioneers | W 17–16 | 12-13 | 48.0 | 6 |
| 2022-02-27 | Johns Hopkins University Blue Jays | W 15–10 | 12-8 | 60.0 | 6 |
| 2022-02-23 | Brown Bears | W 14–11 | 18-6 | 75.0 | 8 |
| 2022-02-19 | Ohio State Buckeyes | L 8–20 | 4-11 | 26.7 | 1 |
| 2022-02-13 | Colgate Raiders | W 15–9 | 1-4 | 20.0 | 1 |
| 2022-02-11 | Richmond Spiders | W 13–9 | 16-7 | 69.6 | 10 |
| Split | GP | FO% | GB |
|---|---|---|---|
| Home | 10 | 55.6 | 4.6 |
| Away | 3 | 45.0 | 3.3 |
| vs Conf | 6 | 46.4 | 3.5 |
| Non-conf | 7 | 58.3 | 5.0 |